Members

Eman Alammari - MSc Precision Medicine, research project student

Project: The impact of dilated cardiomyopathy on cell-type specific gene expression

Kate Campbell - PhD Student

Project: Drosophila based screening to replace mammalian systems to identify the functional role of candidate genes in controlling muscle dyadic architecture - co-supervised with Prof Andrew Trafford, Dr Kat Dibb, Prof Andreas Prokop.

Maciej Drzal - PhD Student

Project: Multi-omic profiling of the hypertensive kidney - co-supervised with Prof. Maciej Tomaszewski.

James Eales - Lecturer in Cardiovascular Computational Biology and Principal Investigator

We run in-silico experiments to investigate the biological mechanisms causal to cardiovascular disease. We do multiomics, deep-learning, molecular diagnostics, translational research, single-cell transcriptomics. We are interested in understanding more about the biology behind hypertension, coronary artery disease, kidney histopathology and alternative splicing.

Email - james.eales@manchester.ac.uk
Affiliation - Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health.
Location - AV Hill Building, Manchester
Twitter - @EalesJames

Sushant Saluja - PhD Student

Project: Therapeutic targeting of blood pressure-associated kidney genes - co-supervised with Prof Maciej Tomaszewski.

David Scannali - Research Assistant

Currently working on the transcriptomics of heart failure and sex chromosome aneuploidy.
Former PhD student Transcriptomics and epigenomics of chronic kidney disease - co-supervised with Dr Sabu Abraham, Dr Nick Ashton and Prof Maciej Tomaszewski.

Yong Sun - PhD Student

Project: Insights into mechanisms of chronic kidney disease from human tissue multi-omics - co-supervised with Prof Maciej Tomaszewski.

Steph Brown - PhD Student

Project: Sequence-based deep learning models for prioritisation of disease-associated non-coding variants in cardiovascular disease - co-supervised with Prof. Theodore Papamarkou.

Qi Wang - PhD Student

Project: A deep learning model of tissue-specific alternative splicing in cardiovascular disease genes - co-supervised with Prof. Theodore Papamarkou.

Email - qi.wang-41@postgrad.manchester.ac.uk